郭晨云
职称:副教授
电话:
Email:guochy78@xmu.edu.cn
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首页 >> 科研团队 >> 郭晨云  简介
:: 个人简历

山西大学生物科学与技术学院生物化学理学学士(1996-2000);

山西大学生物技术研究所生物化学与分子生物学理学博士(2000-2005)

中科院上海药物研究所助理研究员(2005-2008);

美国马里兰大学化学与生物化学系博士后(2008-2010);

厦门大学化学与化工学院化学生物化学系副教授(2010-).

:: 工作方向
蛋白质和多肽的结构与功能研究
:: 承担的基金

 国家自然科学基金青年项目:RKIP磷酸化交叉调控MAPK信号通路与GPCR信号通路的分子机制和结构基础(No. 30900233)

上海市自然科学基金:海洋活性多肽vi6A和vi6B的结构与功能研究   (No. 07ZR14135 )
:: 代表性文章

1、C. Guo, R.Godoy-Ruiz, V.Tugarinov, High resolution measurement of methyl 13C(m)-13C and 1H(m)-13C(m)   residual dipolar couplings in large proteins. J. Am. Chem. Soc. 132:13984 (2010).

2、C.Guo, Y. Lian, Q, Liu, J. Liu, Y. Zhang, D. Lin, Soluble expression and characterization of a  mouse  epididymis- specific protein lipocalin6, Protein Expr. Puri, 69: 64 (2010)

3、C. Guo, V. Tugarinov, Selective 1H-13C NMR spectroscopy of methyl groups in  residually protonated   samples of large proteins,  J. Biomol. NMR, 46:127 (2010).

4、C. Guo, C. Geng, V. Tugarinov,Selective backbone labeling of proteins using 1,2-13C2 -pyruvate as  carbon   source,  J. Biomol. NMR. 44: 167(2009).

5、C. Guo, H. Diao, Y. Lian, H. Yu, H. Gao, Y. Zhang, D. Lin, Recombinant expression  and characterization of  an epididymis-specific antimicrobial peptide BIN1b / SPAG11E, J. Biotechnol., 139: 33 (2009)

6、C. Guo, D. Zhang, V. Tugarinov, A NMR experiment for simultaneous TROSY - based   detection   of  amide  and methyl groups in large proteins,  J. Am. Chem. Soc. 130: 10872 (2008)

7、C. Guo, V. Tugarinov, Identification of HN-Methyl NOEs in large proteins using  simultaneous  amide-methyl  TROSY-based Detection, J. Biomol. NMR, 43: 21 (2008)

8、C. Guo, Z. Li, J. Yuan, Preparation of an immunoadsorbent coupled with a recombinant antigen to remove anti-acetylcholine receptor antibodies in abnormal serum, J. Immunol. Method, 303:142 (2005)

9、C. Guo, Z. Li, Y. Shi, et al, Intein-mediated fusion expression, high efficient refolding and one-step   purification of gelonin toxin, Protein Expr. Puri.,   37: 361 (2004)

:: 获奖情况
:: 学术职务

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