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嘉庚化学讲座:Sialoglycan Microarrays for Cancer Marker and Virus Binding Studies
【来源】:本站原创 【发表时间】:2013-6-24 【浏览次数】:
题 目: Sialoglycan Microarrays for Cancer Marker and Virus Binding Studies

讲座人: Prof. Xi Chen(我校化学系90级校友), Department of Chemistry, University of California-Davis, USA
时 间: 2013年6月27日(星期 四)上午10:30 – 12:00
地 点: 卢嘉锡楼二楼报告厅(202)

内容简介:

Glycan microarrays have been increasingly used as an effective high-throughput platform to elucidate the ligand specificity of various glycan-binding proteins and microorganism and to profile levels of specific anti-glycan antibodies in different populations. Chemoenzymatic methods that combine the flexibility of chemical synthesis and the specificity and high efficiency of enzymatic catalysis have been used as efficient approaches for producing focused sialoglycan libraries. These compounds have been used to construct sialoglycan microarrays for identifying anti-glycan antibody-based cancer markers and elucidating the binding specificities of lectins and viruses.