首页 >> 师资队伍 >> 韩守法
:: 个人简历

北京大学化学系, 获学士学位(1996)

中国科学院北京化学研究所, 获得高分子化学与物理专业硕士学位(1999)

Toledo大学, 获得生物化学专业博士(2003)

The Scripps Research Institute博士后(2003-2006)

厦门大学化学生物学系教授,博导(2006-今)

:: 工作方向

1. 化学生物学,研究包括糖蛋白所含的唾液酸的功能,如IgG;

2. 化学或酶催化法引入非天然唾液酸到蛋白上改善其生物活性;

3. 酶催化法合成含有唾液酸的小分子或纳米材料探针把小分子药物或蛋白质运载到特定的细胞内。

:: 承担的基金
:: 代表性文章

1、Han. S., Collins, B. E., Bengtson. P., and Paulson, J. C., Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking, Nature Chemical Biology, 1, 93-97, 2005
2、Han. S., Collins, B. E., Bengtson. P., and Paulson, J. C.,, Synthesis of 9-Substituted Sialic Acids As Probes for CD22-Ligand Interactions on B cells, Frontiers in Modern Carbohydrate Chemistry, 2007, 2-13
3、Collins, B.E., Blixt, O., Han, S. Duong, B., Li, H., Nathan, J.K., Bovin, N., and Paulson, J.C. (2006) High Affinity Ligand Probes of CD22 Overcome the Threshold set by cis Ligands to Allow for Binding, Endocytosis and Killing of B cells. Journal of Immunology, 2006, 177, 2994-3003
4、Han. S., Moore. R. A., and Viola, R. E., A facile synthesis of a difluoromethylene analog of b-aspartyl phosphate for Inhibition of L-aspartate-b-semialdehyde dehydrogenase, Synlett, 6, 845-846, 2003
5、Han. S., and Viola, R. E.,, A spectrophotometric assay of Arginase, Analytical Biochemistry, 295(1), 117-119, 2001

:: 获奖情况
:: 学术职务