| :: 个人简历 |
|
2010年6月至今，厦门大学化学化工学院，教授，博导 2008年-2010年，斯坦福大学医学院，博士后 2004年-2008年，香港科技大学化学系，博士 2000年-2004年，南京大学化学系，理学学士 |
| :: 工作方向 |
| :: 承担的基金 |
(1) 国家自然科学基金优秀青年科学基金项目，生物功能无机纳米材料 (2) 国家自然科学基金面上项目，高性能磁共振造影剂的设计合成及活体成像研究 (3) 国家自然科学基金面上项目，高性能磁性纳米药物的构建及其肿瘤诊疗一体化应用研究 (4) 国家重大科学研究计划课题，可控特性纳米材料的设计合成及其诱导自噬的相关性研究 (5) 国家自然科学基金创新研究群体项目，谱学分析（负责人：江云宝） (6) 国家自然科学基金重点项目，以肝癌干细胞为靶标的多模态成像导航在肝癌介入治疗的研究（参加） (7) 国家重点基础研究发展计划课题，乳腺癌分子分型标志物的多功能分子探针研究（参加） |
| :: 代表性文章 |
(1) Zhu, X. L.; Tang, X.; Lin, H. Y.; Shi, S.; Xiong, H.; Zhou, Q.; Li, A.; Wang, Q.; Chen, X.; Gao, J. H.* A Fluorinated Ionic Liquid-Based Activatable19F MRI Platform Detects Biological Targets. Chem 2020, 6, DOI: 10.1016/j.chempr.2020.01.023. (2) Sun, C. J.; Lin, H. Y.; Gong, X. Q.; Yang, Z.; Mo, Y.; Chen, X.; Gao, J. H.* DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators. J. Am. Chem. Soc.2020, 142, 198-206. (3) Tang, X.; Gong, X. Q.; Li, A.; Lin, H. Y.; Peng, C.; Zhang, X.; Chen, X.; Gao, J. H.* Cascaded Multiresponsive Self-Assembled19F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification. Nano Lett.2020, 20, 363-371. (4) Zhou, Z.; Yang, L.; Gao, J. H.;* Chen, X.* Structure–Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging. Adv. Mater.2019, 31, 1804567. (5) Zhang, Y. J.;* Zhang, L.; Gao, J. H.;* Wen, L. P.* Pro-Death or Pro-Survival: Contrasting Paradigms on Nanomaterial-Induced Autophagy and Exploitations for Cancer Therapy. Acc. Chem. Res.2019, 52, 3164-3176. (6) Wei, R.; Gong, X.; Lin, H.; Zhang, K.; Li, A.; Liu, K.; Shan, H.; Chen, X.; Gao, J. H.* Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery. Nano Lett.2019, 19, 5394-5402. (7) Li, A.; Tang, X.; Gong, X.; Chen, H.; Lin, H. Y.; *Gao, J. H.* A Fluorinated Bihydrazide Conjugate for Activatable Sensing and Imaging of Hypochlorous Acid by19F NMR/MRI. Chem. Commun.2019, 55, 12455-12458. (8) Yang, Z.; Lin, H.; Huang, J.; Li, A.; Sun, C.; Richmond, J.; Gao, J. H.* A Gadolinium-Complex-Based Theranostic Prodrug for In Vivo Tumour-Targeted Magnetic Resonance Imaging and Therapy. Chem. Commun.2019, 55, 4546-4549. (9) Yang, L.; Wang, Z.; Ma, L.; Li, A.; Xin, J.; Wei, R.; Lin, H.; Wang, R.; Chen, Z.; Gao, J. H.* The Roles of Morphology on the Relaxation Rates of Magnetic Nanoparticles. ACS Nano2018, 12, 4605-4614. (10) Zhou, Z.; Wu, C.; Liu, H.; Zhu, X.; Zhao, Z.; Wang, L.; Xu, Y.; Ai, H.; Gao, J. H.* Surface and Interfacial Engineering of Iron Oxide Nanoplates for Highly Efficient Magnetic Resonance Angiography. ACS Nano2015, 9, 3012-3022. (11) Zhao, Z.; Wang, X.; Zhang, Z.; Zhang, H.; Liu, H.; Zhu, X.; Li, H.; Chi, X.; Yin, Z.; Gao, J. H.* Real-Time Monitoring of Arsenic Trioxide Release and Delivery by Activatable T1Imaging. ACS Nano2015, 9, 2749-2759. (12) Zhou, Z.; Zhao, Z.; Zhang, H.; Wang, Z.; Chen, X.; Wang, R.; Chen, Z.; Gao, J. H.* Interplay between Longitudinal and Transverse Contrasts in Fe3O4Nanoplates with (111) Exposed Surfaces. ACS Nano2014, 8, 7976-7985. (13) Zhao, Z. H.; Zhou, Z. J.; Bao, J. F.; Wang, Z. Y.; Hu, J.; Chi, X. Q.; Ni, K. Y.; Wang, R. F.; Chen, X. Y.; Chen, Z.; Gao, J. H.* Octapod Iron Oxide Nanoparticles as High-Performance T2Contrast Agents for Magnetic Resonance Imaging. Nat. Commun.2013, 4, 2266. (14) Zhou, Z. J.; Wang, L. R.; Chi, X. Q.; Bao, J. F.; Yang, L. J.; Zhao, W. X.; Chen, Z.; Wang, X. M.; Chen, X. Y.; Gao, J. H.* Engineered Iron-Oxide-Based Nanoparticles as Enhanced T1Contrast Agents for Efficient Tumor Imaging. ACS Nano2013, 7, 3287-3296. (15) Zhou, Z. J.; Huang, D. T.; Bao, J. F.; Chen, Q. L.; Liu, G.; Chen, Z.; Chen, X. Y.; Gao, J. H.* A Synergistically Enhanced T1-T2Dual-Modal Contrast Agent. Adv. Mater.2012, 24, 6223-6228. (16) Gao, J. H.; Gu, H. W.; Xu, B.* Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications. Acc. Chem. Res.2009, 42, 1097-1107. (17) Gao, J. H.; Liang, G. L.; Cheung, S. C.; Pan, Y.; Kuang, Y.; Zhao, F.; Zhang, B.; Zhang, X. X.; Wu, E. X.; Xu, B.* Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent. J. Am. Chem. Soc.2008, 130, 11828-11833. (18) Gao, J. H.; Zhang, W.; Huang, P. B.; Zhang, B.; Zhang, X. X.; Xu, B.* Intracellular Control of Fluorescent Magnetic Nanoparticles. J. Am. Chem. Soc.2008, 130, 3710-3711. (19)Gao, J. H.; Zhang, B.; Gao, Y.; Pan, Y.; Zhang, X. X.; Xu, B.* Fluorescent Magnetic Nanocrystals by Sequential Addition of Reagents in a One-Pot Reaction: A Simple Preparation for Multifunctional Nanostructures. J. Am. Chem. Soc.2007, 129, 11928-11935. (20) Gao, J. H.; Liang, G. L.; Zhang, B.; Kuang, Y.; Zhang, X. X.; Xu, B.* FePt@CoS2Yolk-shell Nanocrystals as a Potent Agent to Kill HeLa Cells. J. Am. Chem. Soc.2007, 129, 1428-1433. |
| :: 获奖情况 |
香港青年科学家奖 (2007) 教育部“新世纪优秀人才支持计划”（2010） 福建省“闽江学者”特聘教授（2011） 国家基金委优秀青年科学基金项目资助（2012） 福建省杰出青年科学基金资助（2012） 福建省青年拔尖创新人才（2014） 中国化学会青年化学奖（2014） 霍英东教育基金会青年教师奖（2016）
|
| :: 学术职务 |